Tuesday, July 29, 2025

Gleneagles Connect #65

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Treatment for Peritoneal Cancer - Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
 
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a high-concentration treatment for patients with primary peritoneal cancer and peritoneal metastasis originating from the malignancy of other organs such as ovaries and stomach. It is a one-time combined treatment with cytoreductive surgery. While the patient is still under anaesthesia, surgeons first remove all visible tumours through surgery, then deliver heated chemotherapy into the patient's peritoneal cavity to eliminate any remaining invisible tumours.
 
Compared to conventional systemic treatments such as chemotherapy, during HIPEC, drug solution is directly delivered into the abdominal cavity and heated and recirculated, which increases the penetration of drugs to reach and kill cancer cells. HIPEC causes relatively fewer side effects as the treatment is confined within the abdominal cavity. A study revealed that, for stage 3 ovarian cancer, the median overall survival was 12 months longer among the patients who received HIPEC than among those who did not receive HIPEC.
 
Watch the video to explore more about the HIPEC treatment from the sharing by Dr Ng Tong-yow, Director of Peritoneal Malignancy Treatment Centre at Gleneagles.
 
腹腔癌治療 - 腹腔溫熱灌注化療
 
腹腔溫熱灌注化療(HIPEC)是一種高度集中的治療,適用於腹膜原位癌及卵巢癌、胃癌等其他癌症擴散至腹膜的患者。HIPEC是配合腫瘤細胞減滅手術的一次性複合治療,外科醫生先透過手術清除所有肉眼看得見的腫瘤,在病人仍處於麻醉狀態時,即時將經加熱的化療藥物並注入腹腔,清除肉眼不可見的癌細胞。
 
有別於傳統化療等全身性藥物治療,進行HIPEC時,化療藥物直接注入腹腔,過程中不斷加熱及循環灌注,可加強藥物對癌細胞的滲透性並殺滅癌細胞。此外,HIPEC的治療範圍僅限於腹腔內從而減少產生副作用。有研究顯示,接受手術配合HIPEC治療的第三期卵巢癌病人,相對於只接受手術的病人,總存活期中位數多12個月。
 
立即觀看影片,由港怡醫院腹膜腫瘤治療中心總監吳東耀醫生詳細講解HIPEC治療方案。
Gleneagles' column on Sky Post    
 
Gleneagles' Consultant in Rheumatology Dr Yeung Wan-yin shared about information on urticaria. Another educational piece on men's sexual health was contributed by Gleneagles' Resident Doctor Dr Chan Chim-yiu.

Read on for the full articles (in Chinese only):  
🔎
Urticaria
🔎Men's sexual health


晴報專欄「醫語怡情」

港怡醫院風濕病科顧問醫生楊韻姸醫生分享關於蕁麻疹(俗稱「風癩」)的資訊;港怡醫院駐院醫生陳佔耀醫生亦透過專欄文章,提醒大眾關注男士性健康 。

What is Epilepsy?

Epilepsy, commonly known as "seizures", is a prevalent neurological disorder caused by abnormal electrical discharges in brain cells, leading to temporary brain dysfunction. It is primarily divided into two types, namely focal epilepsy and generalised epilepsy. The prevalence of epilepsy ranges from 0.5% to 1%, with infants and the elderly being the high-risk groups. Symptoms include recurrent seizures, abnormal behaviour, or loss of consciousness, with causes potentially involving genetics, brain hypoxia, infections, or trauma. Factors such as sleep deprivation, emotional stress, or physical discomfort may also trigger the condition.

Identifying Epilepsy Through Elusive Symptoms

Generalised epilepsy is more common in children, with patients experiencing limb convulsions, stiffness, eye-rolling, cyanosis, or incontinence during seizures, and usually lasting less than five minutes. Absence epilepsy is often overlooked, as patients may only exhibit brief moments of unresponsiveness, appearing inattentive or zoning-out, which can be mistaken as misbehaviour or lack of focus. Dr Yuen Chi-lap, Consultant in Paediatrics at Gleneagles Hospital Hong Kong, emphasises that distinguishing epilepsy from tic disorders (the latter can be briefly controlled and do not occur during sleep) is crucial Parents should seek medical attention promptly if they notice any unusual behaviour in their children.


Managing the Condition to Restore Health

Approximately three-quarters of patients can effectively control their condition with medication. Common treatment options include medication, surgical intervention, and ketogenic diets, tailored to individual needs. The ketogenic diet (90% fat, 10% carbohydrates and protein daily) produces ketones through fat metabolism, regulating brain neurotransmission to reduce abnormal brain waves and lower seizure risks. Dr Yuen stresses the importance of early diagnosis and personalised treatment, while calling for societal support to help patients return to a normal life.

🔎Click here to read the article (in Chinese only) where Dr Yuen Chi-lap explains epilepsy, diving into its causes and treatment options.

甚麼是腦癇症?

腦癇症(俗稱「發羊吊」)是一種常見的腦科疾病,源於腦神經細胞異常放電,導致大腦神經功能短暫紊亂。其主要分為「局部性腦癇症」和「全身性腦癇症」兩大類。每個人在一生中患腦癇症的機率介乎0.5%至1%,嬰幼兒及長者為高危群組。症狀包括反覆抽筋、行為異常或失去知覺。成因可能涉及遺傳、腦部缺氧、感染或創傷,而睡眠不足、情緒波動、身體不適等因素,也有機會誘發疾病。

從症狀分辨腦癇症

「全身性腦癇症」在兒童中較常見,患者發作時可能出現四肢抽搐、僵直、眼球上翻、嘴唇發紫或失禁,持續時間通常少於5分鐘。「失神性腦癇」則容易被忽略,患者可能只出現數秒的失神,看似不在焉或「遊魂」,容易被誤以為是頑皮或注意力不足。港怡醫院兒科顧問醫生袁志立表示,區分腦癇症與抽動症(後者可短暫控制且不於睡眠時發作)至關重要,如家長發現兒童任何異常行為,應及早求醫。


控制病情重拾健康

約四分之三的腦癇症患者可透過藥物有效控制病情。常見的治療方案包括藥物治療、手術治療及生酮飲食,具體方案因人而異。生酮飲食(每日90% 脂肪、10% 碳水化合物和蛋白質)透過燃燒脂肪產生「酮體」,調節腦神經傳遞,減少異常腦電波,有助降低復發風險。袁醫生強調,早期診斷與個人化治療的重要性,並呼籲社會支持患者,幫助他們重拾正常生活。

🔎請按此閱讀文章,由袁志立醫生講解腦癇症,深入了解腦癇症的成因及治療方案。

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